Why I don't buy "trajectory of science" arguments

I should say that I am unpersuaded of "trajectory of science" arguments which suggest that as we investigate further we will find greater and greater support for reductionism. Two aspects of the materialistic vision of the world as it has been historically understood are the following: 

1) The universe had no beginning, and has always existed. 

2) The universe is deterministic, and as we do science we will come closer and closer to finding determining causes for everything. 

Now, thanks to the development of the Big Bang theory in the first instance, and quantum mechanics in the second instance, confidence in both of these theses has eroded in comparison to what might have been thought in the early days of the 20th Century. 

Now, of course, naturalists have revised their conception of what is naturalistically acceptable to accommodate a universe with a temporal beginning, and a universe with quantum level indeterminism. But the point is that science frustrated the expectations of what at the time were the expected results of the naturalistic thrust of science. 

With respect to the analysis of mind, I see a lot of bravado about reductive analyses but no real hard evidence that reductions are going to be successful. In fact, given the fact that "the material" or "the natural" has to be defined in terms of the absence of the mental, it looks to me as if reduction of the mental to the physical is logically impossible, and that the more we study things scientifically the more evident this will become.

Bottom line: future science is FUTURE science. Who knows where it will go.